反应 #40355

ord-7a53433ac6064883800fb9189592d274

反应方程式

CCCN1CCCc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc21
Compound 192
CCCN1CCCc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc21
4-Trifluoromethyl-6-propyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one
CC=O
acetaldehyde
CCN1CCCc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc21
4-Trifluoromethyl-6-ethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他This compound was prepared in a similar fashion as

实验过程

This compound was prepared in a similar fashion as that described in Example 84 from Compound 192 (Structure 33 of Scheme VI, where R1═H, n=1) and acetaldehyde. 1H NMR (400 MHz, CDCl3) 11.23 (br. s, 1H), 7.07 (s, 1H), 7.00 (s, 1H), 6.82 (s, 1H), 3.39 (q, 2H, J=7.1), 3.31 (t, 2H, J=5.6), 2.88 (t, 2H, J=6.4), 1.98 (m, 2H), 1.18 (t, 3H, J=7.1).

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07727980B2uspto-grants-2010_06