反应 #3838

反应方程式

4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzene sulfonamide

thiosalicylic acid

→

title compound

收率 95.5%

2-[2-(4-Sulfamoylphenylcarbamoyl)phenyldisulfanyl]benzoic acid

收率 95.5%

溶剂

methanol

tetrahydrofuran

反应条件

后处理

1. 1
   其他This compound was prepared
2. 2
   洗涤The product was washed with ether
3. 3
   其他dried in vacuo

实验过程

This compound was prepared according to the method of Example 132 using a suspension of 0.46 g (1.5 mmol) of 4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzene sulfonamide in a mixture of 15 mL of methanol and 15 mL of tetrahydrofuran, and 0.23 g (1.5 mmol) of thiosalicylic acid. The product was washed with ether and dried in vacuo to give 0.66 g of the title compound, mp 276°-278° C.

来源