反应 #3837

反应方程式

4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzenesulfonamide

2-mercapto-propionylglycine

→

title compound

收率 92.3%

{2-[2-(4-Sulfamoylphenylcarbamoyl)phenyldisulfanyl]propionylamino}-acetic acid

收率 92.3%

反应条件

后处理

1. 1
   其他This compound was prepared
2. 2
   洗涤The product was washed with ether
3. 3
   其他dried in vacuo

实验过程

This compound was prepared according to the method of Example 132 using 0.46 g (1.5 mmol) of 4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzenesulfonamide and 0.25 g (1.5 mmol) of 2-mercapto-propionylglycine. The product was washed with ether and dried in vacuo to give 0.65 g of the title compound, mp 254°-256° C.

来源