反应 #3784

反应方程式

1,2-bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene

hydrobromic acid

→

1,2-bis(2-methyl-3-thienyl)hexafluorocyclopentene

收率 98.0%

溶剂

chloroform

反应条件

后处理

1. 1
   其他to react for 6 hours under refluxing conditions
2. 2
   其他After the completion of the reaction
3. 3
   洗涤the chloroform layer was washed with an aqueous solution of sodium bicarbonate
4. 4
   其他the chloroform was removed under reduced pressures
5. 5
   其他The reaction product was purified by silicagel column chromatogram

实验过程

1,2-bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene (2.16 g, 0.005 mol) was dissolved in chloroform (200 ml) and was allowed to react for 6 hours under refluxing conditions by adding concentrated hydrobromic acid (10 ml) to the solution. After the completion of the reaction, the chloroform layer was washed with an aqueous solution of sodium bicarbonate and the chloroform was removed under reduced pressures. The reaction product was purified by silicagel column chromatogram to give 1,2-bis(2-methyl-3-thienyl)hexafluorocyclopentene (1.8 g, 0.0049 mol).

来源