反应 #3777

反应方程式

triphenylphosphine

3-[4-(4,4-dimethyl-4-ethoxycarbonylbutoxy)phenoxy]propyltriphenylphosphonium bromide

ethyl 2,2-dimethyl-5-[4-(3-bromopropyloxy)phenoxy]pentanoate

→

ethyl 5-[4-(3-hydroxypropyloxy)phenoxy]pentanoate

bromine

triphenylphosphine

溶剂

acetonitrile

acetonitrile

反应条件

后处理

1. 1
   其他was prepared

实验过程

The 3-[4-(4,4-dimethyl-4-ethoxycarbonylbutoxy)phenoxy]propyltriphenylphosphonium bromide used as starting material was prepared by reacting triphenylphosphine in acetonitrile, at reflux, with ethyl 2,2-dimethyl-5-[4-(3-bromopropyloxy)phenoxy]pentanoate, itself obtained from ethyl 5-[4-(3-hydroxypropyloxy)phenoxy]pentanoate and bromine in acetonitrile in the presence of triphenylphosphine.

来源