反应 #361382

反应方程式

2,6-dimethylquinoline

butanesultone

→

4-[2,6-dimethyl-1quinolinio]butanesulfonate

收率 94.3%

溶剂

acetone

反应条件

后处理

1. 1
   温度was cooled with ice for 30 minutes for crystallization
2. 2
   其他The crystals formed
3. 3
   过滤were filtered out
4. 4
   洗涤washed with acetone
5. 5
   其他dried

实验过程

72.3 g (0.46 mol) of 2,6-dimethylquinoline and 188 g (1.4 mol) of butanesultone were heated at 145° C. for 4 hours with stirring. After being cooled to room temperature, 500 ml of acetone was added to the reaction mixture, which was cooled with ice for 30 minutes for crystallization. The crystals formed were filtered out, washed with acetone and dried to obtain 127.3 g of 4-[2,6-dimethyl-1quinolinio]butanesulfonate. The yield of the product was 94%.

来源