反应 #355757

反应方程式

9-ethyl-3-carbazolecarboxaldehyde

hydrazine monohydrate

triethylamine

→

9-ethyl-3-carbazolecarboxaldehyde hydrazone

溶剂

tetrahydrofuran

water

反应条件

后处理

1. 1
   其他equipped with a mechanical stirrer and an addition funnel
2. 2
   workup.STIRRINGthe reaction mixture was stirred at room temperature for 2 hours
3. 3
   过滤A precipitate was collected by filtration
4. 4
   洗涤washed repeatedly with water

实验过程

A quantity of 98% hydrazine monohydrate (50 ml, 1.4 mole, obtained from Aldrich, Milwaukee, Wis.) and 10 ml of triethylamine (obtained from Aldrich, Milwaukee, Wis.) were added to a 250 ml, 2-neck round bottom flask equipped with a mechanical stirrer and an addition funnel. The solution was stirred vigorously at room temperature for a period of 10-15 min. A solution of 9-ethyl-3-carbazolecarboxaldehyde (22.3 g, 0.1 mol, from Aldrich, Milwaukee, Wis.) in 30 ml of tetrahydrofuran (THF) were added slowly to the round bottom flask. After the addition of aldehyde was completed, the reaction mixture was stirred at room temperature for 2 hours. Next, the reaction mixture was diluted with 50 ml of water. A precipitate was collected by filtration and washed repeatedly with water to give crude 9-ethyl-3-carbazolecarboxaldehyde hydrazone, which was used in the next step immediately.

来源