反应 #355735

ord-755455fcd9394111bbc1bd3c8d02519f

反应方程式

Cl.Cl.Nc1c(F)c(N)c(F)c(F)c1F
dihydrochloride
Cc1cc([N+](=O)[O-])ccc1NCCNCCO
2-[2-(4-nitro-2-methylphenylamino)ethylamino]ethanol
Cc1cc(N)ccc1NCCNCCO.Cl.Cl
amine
Cc1cc(N)ccc1NCCNCCO.Cl.Cl
2-[2-(4-amino-2-methylphenylamino)ethylamino]ethanol dihydrochloride

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

The 2-[2-(4-nitro-2-methylphenylamino)ethylamino]ethanol (5) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07445645B2uspto-grants-2008_11