反应 #354918

反应方程式

thiophenol

triethylamine

water

2-amino-6-chloro-5-cyano-1-n-hexyl-4-n-hexylamino pyridinium chloride

→

2-amino-5-cyano-1-n-hexyl-4-n-hexylamino-6-phenylmercapto pyridinium chloride

收率 51.9%

溶剂

ethanol

反应条件

实验过程

3.7 gms (.01 ml) of 2-amino-6-chloro-5-cyano-1-n-hexyl-4-n-hexylamino pyridinium chloride (compound 11 - Table 1) was dissolved in ethanol and 1.1 gm (.01 mole) thiophenol and 1.0 gm (0.01 mole) of triethylamine added. The solution was left 16 hours at room temperature poured into iced water and 2.3 gms (50% yield) of 2-amino-5-cyano-1-n-hexyl-4-n-hexylamino-6-phenylmercapto pyridinium chloride (compound 78 - Table 5) filtered off (MPt 227° -228°C).

来源