反应 #348466

反应方程式

3,5-dinitro-4-chloro-o-toluamide

phosphorus pentoxide

→

desired product

3,5-Dinitro-4-chloro-o-toluonitrile

反应条件

后处理

1. 1
   workup.DISTILLATIONThe resulting nitrile is distilled from the reaction flask
2. 2
   其他Recrystallization of the solidified product from methanol

实验过程

A finely powdered mixture of 15.5 grams (0.051 mole) of 3,5-dinitro-4-chloro-o-toluamide is heated with 12 grams (0.084 mole) of phosphorus pentoxide for 15 minutes at 300° C. to 350° C. The resulting nitrile is distilled from the reaction flask. Recrystallization of the solidified product from methanol gives the desired product as an analytically pure material.

来源