反应 #346849

反应方程式

2,6-dimethylquinoline

butane sultone

→

4-[2,6-dimethyl-1-quinolinio]butane sulfonate

收率 94.3%

溶剂

acetone

反应条件

后处理

1. 1
   温度While cooling
2. 2
   其他crystallization
3. 3
   workup.WAITwas conducted for 30 minutes
4. 4
   过滤The resulting crystal was recovered by filtration
5. 5
   洗涤washed with acetone
6. 6
   其他dried

实验过程

After 72.3 g (0.46 mol) of 2,6-dimethylquinoline and 188 g (1.4 mol) of butane sultone were heated at 145° C. with stirring for 4 hours, the mixture was allowed to cool to room temperature, and 500 ml of acetone was added thereto. While cooling, crystallization was conducted for 30 minutes. The resulting crystal was recovered by filtration, washed with acetone and dried to obtain 127.3 g (yield: 94%) of 4-[2,6-dimethyl-1-quinolinio]butane sulfonate.

来源