反应 #336434

反应方程式

p-cyanoaniIine

4-chloro-3-nitropyridine

→

title compound

收率 86.6%

4-[N-(4-Cyanophenyl)amino]-3-nitropyridine

收率 86.6%

溶剂

ethanol

反应条件

后处理

1. 1
   过滤filtered The solid
2. 2
   workup.ADDITIONwas treated with 150 ml of boiling ethanol
3. 3
   温度cooled in ice
4. 4
   过滤filtered

实验过程

According to the method of J.C.S. Perkin Trans. I, 1979, 135, p-cyanoaniIine (6 894 g, 58.4 mmol) was added to a solution of 4-chloro-3-nitropyridine (9.26 g, 58.4 mmol) in ethanol (200 ml) and the mixture was stirred at room temperature for 18 hours. The resulting yellow suspension was poured into 500 ml of ice-cold dilute ammonia and filtered The solid was treated with 150 ml of boiling ethanol, cooled in ice, and filtered to give the title compound as a bright yellow powder, (12.15 g), m.p. 210°-211° C.

来源