反应 #3173

反应方程式

methacryloyloxyethyl isocyanate

benzyl alcohol

→

benzyloxycarbonylaminoethyl methacrylate

收率 80.6%

溶剂

dioxane

反应条件

后处理

1. 1
   其他reaction at a temperature of 65° C. for 3 hours
2. 2
   workup.DISTILLATIONThe dioxane and excess benzyl alcohol were then distilled off under reduced pressure
3. 3
   workup.ADDITIONThe residue was poured into water
4. 4
   萃取extracted with ethyl acetate
5. 5
   其他dried
6. 6
   workup.DISTILLATIONThe solvent was then distilled off

实验过程

77.5 g of methacryloyloxyethyl isocyanate (Karenzu MOI, available from Showa Denko K.K.) and 60 g of benzyl alcohol were dissolved in 260 g of dioxane. To the solution were then added 5 drops of di-n-butyltin dilaurate. The reaction mixture was then allowed to undergo reaction at a temperature of 65° C. for 3 hours. The dioxane and excess benzyl alcohol were then distilled off under reduced pressure. The residue was poured into water, extracted with ethyl acetate, and then dried. The solvent was then distilled off to obtain 106 g of benzyloxycarbonylaminoethyl methacrylate in the form of colorless oil.

来源