反应 #312646

反应方程式

2-(4-chloro-2,5-difluorophenyl)thieno[3,2-d]pyrimidine-4(1H)-one

phosphorus oxychloride

→

4-chloro-2-(4-chloro-2,5-difluorophenyl)thieno[3,2-d]pyrimidine

反应条件

实验过程

A mixture of 2-(4-chloro-2,5-difluorophenyl)thieno[3,2-d]pyrimidine-4(1H)-one and phosphorus oxychloride was stirred for four hours at 90° C. to give 4-chloro-2-(4-chloro-2,5-difluorophenyl)thieno[3,2-d]pyrimidine.

来源