反应 #3066

反应方程式

ethyl 3-bromo-4-methylbenzoate

NBS

benzoyl peroxide

→

ethyl 3-bromo-4-bromomethylbenzoate

溶剂

CCl4

反应条件

后处理

1. 1
   温度was refluxed for 4 h
2. 2
   过滤processed by filtration and chromatography

实验过程

A mixture of 1.0 mmol of ethyl 3-bromo-4-methylbenzoate, 1.0 mmol NBS, and 0.02 mmol benzoyl peroxide in 5 mL CCl4 was refluxed for 4 h and then processed by filtration and chromatography to provide ethyl 3-bromo-4-bromomethylbenzoate as an oil.

来源