反应 #3029

反应方程式

1-chloro-2,4-dinitrobenzene

sodium carbonate

dioctadecylamine

dimethylformamide

→

N,N-dioctadecyl-2,4-dinitrobenzenamine

收率 87.2%

溶剂

water

反应条件

后处理

1. 1
   温度was heated to 80°-90° C. under a nitrogen atmosphere for 1 h
2. 2
   萃取extracted with ether
3. 3
   洗涤The extracts were washed with water
4. 4
   干燥dried over magnesium sulfate
5. 5
   其他The solvent was removed
6. 6
   其他the solid recrystallized

实验过程

A mixture of 1-chloro-2,4-dinitrobenzene (Aldrich, 2.02 g, 10 mmol), sodium carbonate (1.27 g, 12 mmol), dioctadecylamine (Pfaltz & Bauer, 6.26 g, 12 mmol) and dry dimethylformamide (10 mL) was heated to 80°-90° C. under a nitrogen atmosphere for 1 h. The cooled mixture was diluted with water and extracted with ether. The extracts were washed with water and dried over magnesium sulfate. The solvent was removed and the solid recrystallized to give N,N-dioctadecyl-2,4-dinitrobenzenamine (6.0 g, 87%): mp 55.5°-57.5° C.

来源