反应 #2805

反应方程式

1-chloromethyl-2-vinyl-benzene

sodium iodide

water

→

title compound

收率 95.0%

1-Iodomethyl-2-vinyl-benzene

收率 95.0%

溶剂

acetone

反应条件

后处理

1. 1
   温度Heat
2. 2
   温度at gentle reflux for 30 minutes
3. 3
   温度Cool
4. 4
   萃取extract with pentane (200 mL)
5. 5
   干燥Dry (MgSO4)
6. 6
   其他evaporate the solvent in vacuo

实验过程

Dissolve 1-chloromethyl-2-vinyl-benzene (4.0 g, 26 mmol) in acetone (100 mL) and add sodium iodide (4.5 g, 30 mmol). Heat at gentle reflux for 30 minutes. Cool, add water (150 mL) and extract with pentane (200 mL). Dry (MgSO4) and evaporate the solvent in vacuo to give the title compound (95%).

来源