反应 #2756

反应方程式

Tri-o-thymotide

Methyl bromide

→

Tri-o-thymotide methyl bromide

溶剂

2,2,4-trimethylpentane

反应条件

后处理

1. 1
   workup.ADDITIONthe hot solution was introduced into the high pressure autoclave
2. 2
   过滤The crystals were filtered off
3. 3
   洗涤washed 3 times with cold 2,2,4-trimethylpentane
4. 4
   其他The crystals were then dried in the drying cabinet at 50° C.

实验过程

Tri-o-thymotide (25 g) was dissolved in 2,2,4-trimethylpentane (50 ml) at 100° C. and the hot solution was introduced into the high pressure autoclave. Methyl bromide was added to the autoclave until a pressure of 200 bar was reached. The high pressure autoclave was then kept for 2 hours at 110° C. and the solution was then cooled down to room temperature within 5 days. The crystals were filtered off and washed 3 times with cold 2,2,4-trimethylpentane. The crystals were then dried in the drying cabinet at 50° C.

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