反应 #2607

反应方程式

4-amino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(2-methoxyphenyl)benzamide

tertbutyl isocyanate

→

title compound

收率 77.6%

4-(tert-Butylureido)-N-{2-[4-(4-fluorobenzoyl)-piperidino]ethyl}-N-(2-methoxyphenyl)benzamide

收率 77.6%

反应条件

实验过程

Using 4-amino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(2-methoxyphenyl)benzamide (77.7 mg, 0.164 mmol) and tertbutyl isocyanate (0.022 ml, 0.196 mmol), the procedure of inventive Example 144 was repeated to obtain 72.9 mg (77.6%) of the title compound in a colorless oily form.

来源