反应 #2507900

ord-66886c53d42c48a2a2ef5c8a72e6392e

反应方程式

[K]
potassium
COc1cc([N+](=O)[O-])ccc1O
2-methoxy-4-nitrophenol
BrCCn1cccc1
1-(2-bromoethyl)-1H-pyrrole
COc1cc(N)ccc1OCCn1cccc1
title compound
收率 76.0%
COc1cc(N)ccc1OCCn1cccc1
4-(2-(1H-pyrrol-1-yl)ethoxy)-3-methoxyaniline
收率 76.0%

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

Following procedure described in step A of Example 18, the title compound was prepared from the potassium salt of 2-methoxy-4-nitrophenol and 1-(2-bromoethyl)-1H-pyrrole in 76% yield. MS (ESI) 233 (M+H)+.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07956049B2uspto-grants-2011_06