反应 #2460328

反应方程式

10-(4-butylphenyl)-10H-phenothiazine

diphenyliodonium hexafluorophosphate

→

10-(4-butylphenyl)-5-phenyl-10H-phenothiazin-5-ium hexa-fluorophosphate

溶剂

ether

反应条件

后处理

1. 1
   温度Upon cooling to ambient temperature
2. 2
   workup.ADDITIONwas added
3. 3
   洗涤washed with ether
4. 4
   过滤collected by filtration
5. 5
   洗涤washed three times with ether
6. 6
   其他Without further purification
7. 7
   其他it was isolated in 98.2% (2.36 g)
8. 8
   其他yield as a pale yellow solid

实验过程

A mixture of 10-(4-butylphenyl)-10H-phenothiazine (83) (1.44 g, 4.34 mmol), diphenyliodonium hexafluorophosphate (1.85 g, 4.34 mmol) and copper (I) benzoate (0.10 g) was heated at 120° C. for 3 hours under nitrogen. Upon cooling to ambient temperature, the mixture was transferred to a mortar-and-pestle and 50 ml of ether was added. The solid was finely powdered, washed with ether, collected by filtration and washed three times with ether. Without further purification, it was isolated in 98.2% (2.36 g) yield as a pale yellow solid.

来源