反应 #2460319

反应方程式

α,α′-dichloro-p-xylene

triethyl phosphite

→

tetraethyl p-xylylenebisphosphonate

溶剂

反应条件

后处理

1. 1
   其他white crystals were formed immediately
2. 2
   温度Then the mixture was cooled at 0° C.
3. 3
   其他the product was collected
4. 4
   洗涤washed three times with 40 ml of hexanes
5. 5
   其他isolated in 94.4% (40.8 g)
6. 6
   其他yield

实验过程

A mixture of α,α′-dichloro-p-xylene (20 g, 0.114 mol) and triethyl phosphite (60 ml) was refluxed at 180° C. overnight. 80 ml of hexanes was added, and white crystals were formed immediately. Then the mixture was cooled at 0° C., and the product was collected, washed three times with 40 ml of hexanes and isolated in 94.4% (40.8 g) yield.

来源