反应 #2383818

反应方程式

ethyl acrylate

1-nitrohexane

K2CO3

→

methyl 4-nitrononanoate

溶剂

Et2O

反应条件

后处理

1. 1
   其他is sonicated for 5 h
2. 2
   过滤The reaction mixture is filtered
3. 3
   萃取extracted with brine
4. 4
   干燥dried over Na2SO4 (anhydrous)
5. 5
   过滤filtered
6. 6
   浓缩concentrated under reduced pressure
7. 7
   其他to give a yellow liquid
8. 8
   其他The product is purified by column chromatography

实验过程

A suspension of ethyl acrylate, 1-nitrohexane, K2CO3, and Aliquat 336 (6 drops) is sonicated for 5 h. To the reaction is added Et2O. The reaction mixture is filtered, extracted with brine, dried over Na2SO4 (anhydrous), filtered, and concentrated under reduced pressure to give a yellow liquid. The product is purified by column chromatography to give methyl 4-nitrononanoate.

来源