反应 #2383791

反应方程式

4-Methyl-7-nitro-2,3,4,5-tetrahydro-1,4-benzoxazepine

→

4-Methyl-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-ylamine

溶剂

methanol

Pd-C

反应条件

后处理

1. 1
   过滤After 1 h the mixture was filtered through glass
2. 2
   其他evaporated to an oil which

实验过程

4-Methyl-7-nitro-2,3,4,5-tetrahydro-1,4-benzoxazepine (1.52 g, 6.0 mmol) was dissolved in methanol (100 ml) and hydrogenated at 50 psi in the presence of a catalytic quantity of 10% Pd-C. After 1 h the mixture was filtered through glass and evaporated to an oil which was used immediately in the next step.

来源