反应 #2383763

ord-dd422b610fdf444eaffdb5e45e3e760d

反应方程式

Cc1c[nH]nc1C
3,4-dimethylpyrazole
C=O
formalin
Cc1cn(CO)nc1C
solid
收率 95.0%
Cc1cn(CO)nc1C
N-hydroxymethyl-3,4-dimethylpyrazole
收率 95.0%

溶剂

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他Water and methanol were then evaporated

实验过程

96 g (1.0 mol) of 3,4-dimethylpyrazole in 50 ml of methanol were dissolved in 100 g (1.0 mol) of formalin solution (30%) at room temperature. Water and methanol were then evaporated. The title compound remained as a white solid (yield 95%).

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US06488734B1uspto-grants-2002_12