反应 #2358506

反应方程式

DL-valine

N-benzoyl-L-alanine

→

L-valine N-benzoyl-L-alanine

收率 94.2%

溶剂

water

反应条件

后处理

1. 1
   其他to form a clear solution
2. 2
   温度The solution was cooled slowly to room temperature
3. 3
   其他The precipitated crystals were then separated by filtration
4. 4
   洗涤washed with 50 mL of deionized water
5. 5
   其他dried

实验过程

Twenty four grams of DL-valine and 19.3 g of N-benzoyl-L-alanine were suspended in 200 mL of deionized water. The suspension was heated to 95° C. to form a clear solution, to which 0.2 g of salicylaldehyde was added. The solution was cooled slowly to room temperature and stirred for another 48 hours at 25° C. The precipitated crystals were then separated by filtration, washed with 50 mL of deionized water, and dried to obtain 29.2 g of crystalline L-valine N-benzoyl-L-alanine complex (L-valine to N-benzoyl-L-alanine molar ratio of 1:1).

来源