反应 #2348138

反应方程式

phytanic acid

thionyl chloride

→

phytanic acid chloride

收率 94.4%

溶剂

methylene chloride

反应条件

后处理

1. 1
   workup.ADDITIONwas added dropwise at room temperature
2. 2
   workup.ADDITIONAfter the completion of dropwise addition
3. 3
   温度the mixture was refluxed for 1 hour
4. 4
   浓缩concentrated under reduced pressure

实验过程

Under a nitrogen atmosphere, one drop of pyridine was added to 2.0 g of phytanic acid and 10 ml of methylene chloride, and 1.14 g of thionyl chloride was added dropwise at room temperature. After the completion of dropwise addition, the mixture was refluxed for 1 hour, and then concentrated under reduced pressure to obtain about 2 g of phytanic acid chloride.

来源