反应 #2335047

反应方程式

2-cyano-5-formylthiophene

benzoylmethylenetriphenylphosphorane

→

3-(5-cyano-2-thienyl)-1-phenyl-2-propen-1-one

收率 56.6%

溶剂

tetrahydrofuran

反应条件

后处理

1. 1
   温度was refluxed for 30 minutes
2. 2
   其他The reaction mixture was evaporated in vacuo

实验过程

A mixture of 2-cyano-5-formylthiophene (4 g) and benzoylmethylenetriphenylphosphorane (11.09 g) in tetrahydrofuran (40 ml) was refluxed for 30 minutes. The reaction mixture was evaporated in vacuo to give 3-(5-cyano-2-thienyl)-1-phenyl-2-propen-1-one (3.95 g).

来源