反应 #2329028

反应方程式

hydrochloric acid

4-t-butylphthalic anhydride

t-butylbenzene

Aluminum chloride

→

benzoic acid

收率 64.0%

4-t-butyl-2-[4-t-butylbenzoyl)benzoic acid

收率 64.0%

溶剂

dichloroethane

反应条件

后处理

1. 1
   workup.ADDITIONAdded into a 500 ml three-necked flask under the environment of argon
2. 2
   workup.ADDITIONAfter the addition, they
3. 3
   其他After the reaction, ice
4. 4
   workup.ADDITIONwas added gradually
5. 5
   过滤After the precipitates were filtered
6. 6
   洗涤they were thoroughly washed

实验过程

Added into a 500 ml three-necked flask under the environment of argon were 4-t-butylphthalic anhydride 36 g (176 mmole), t-butylbenzene 27 g (200 mmole) and dichloroethane 100 ml. The mixture was cooled to 0° C. Aluminum chloride 56 g (420 mmole) was added gradually to them. After the addition, they were stirred at room temperature overnight. After the reaction, ice was added gradually followed by the addition of concentrated hydrochloric acid. After the precipitates were filtered, they were thoroughly washed to give the benzoic acid substance 32 g (yield 64%, white powder).

来源