反应 #2329005

反应方程式

5-(6-methoxy-1,3-benzoxazol-2-yl)-2-fluoropyridine

2-dimethylamino-pyrimidine-5-carbaldehyde

methyl 4-amino-3-hydroxybenzoate

→

title compound

收率 72.3%

Methyl 2-[2-(dimethylamino)pyrimidin-5-yl]-1,3-benzoxazole-6-carboxylate

收率 72.3%

反应条件

实验过程

The synthesis was performed according to the procedure described for 5-(6-methoxy-1,3-benzoxazol-2-yl)-2-fluoropyridine starting with 180 mg of 2-dimethylamino-pyrimidine-5-carbaldehyde and 200 mg of methyl 4-amino-3-hydroxybenzoate to give 256.8 mg of the title compound.

来源