反应 #2320161

反应方程式

product

4-[3-(azidomethyl)pyridin-2-yl]morpholine

→

product

收率 78.0%

(2-morpholin-4-ylpyridin-3-yl)methylamine

收率 78.0%

溶剂

methanol

反应条件

后处理

1. 1
   过滤the reaction mixture was filtered through celite and
2. 2
   浓缩concentrated

实验过程

To a solution of the product from Example 98A (0.62 g) in methanol (10 ml) was added Pd/C (0.06 g) under N2 atmosphere. The reaction mixture was stirred at room temperature under H2 atmosphere. After 6 hours, the reaction mixture was filtered through celite and concentrated to yield 0.42 g (78%) of product. MS (ESI+) m/z 194 (M+H)+;

来源