反应 #2320104

ord-3e3e36bfa43f4b0691fec661b4d2f193

反应方程式

Clc1ccc(Br)cc1Cl
4-bromo-1,2-dichlorobenzene
CCCN1[C@H](C)CNC[C@@H]1C
cis-2,6-dimethyl-1-propyl-piperazine
Cl
HCl
CCCN1[C@H](C)CN(c2ccc(Cl)c(Cl)c2)C[C@@H]1C
cis-4-(3,4-dichloro-phenyl)-2,6-dimethyl-1-propyl-piperazine

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他the title compound was recovered by the procedure
  2. 2
    其他described in Preparation 9

实验过程

Beginning with 4-bromo-1,2-dichlorobenzene and cis-2,6-dimethyl-1-propyl-piperazine, the title compound was recovered by the procedure described in Preparation 9: m.p. 225° C. (HCl), MS m/z (rel. intensity, 70 eV)) 301 (M+, 24), 271 (64), 112 (bp), 70 (47), 56 (53).

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: USRE041315E1uspto-grants-2010_05