反应 #2314350

反应方程式

5,6-Dichloro-1,2-phenylenediamine

isopropyl isothiocyanate

dicyclohexyl carbodiimide

→

solid

收率 60.0%

5,6-Dichloro-N-(1-methylethyl)-1H-benzimidazol-2-amine

收率 60.0%

溶剂

pyridine

反应条件

后处理

1. 1
   其他The product was recrystallized from acetonitrile

实验过程

5,6-Dichloro-1,2-phenylenediamine (0.61 g, 3.4 mmol), isopropyl isothiocyanate (0.39 g, 3.8 mmol), dicyclohexyl carbodiimide (1.06 g, 5.14 mmol) and pyridine (10 L) were used according to general procedure I. The product was recrystallized from acetonitrile to afford a tan solid (0.46 g, 60%); m.p. 218-220° C.

来源