反应 #2314338

反应方程式

Diethyl (4-methoxyphenylaminomethylene)malonate

phenyl ether

→

ethyl 6-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylate

收率 44.7%

溶剂

diethyl ether

反应条件

后处理

1. 1
   其他preheated to 250° C
2. 2
   温度Heating
3. 3
   温度to cool
4. 4
   其他the precipitate is collected
5. 5
   洗涤rinsed with diethyl ether
6. 6
   其他dried

实验过程

Diethyl (4-methoxyphenylaminomethylene)malonate (5.18 g, 17.9 mmol) is added to phenyl ether (22 mL) preheated to 250° C. Heating is continued for 70 minutes. The reaction mixture is allowed to cool, diethyl ether is added, and the precipitate is collected, rinsed with diethyl ether and dried to afford 1.98 g of ethyl 6-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylate.

来源