反应 #2314332

反应方程式

N-Mono[4-(diethylamino)-salicylidene]-1,2-phenylenediamine

N-Mono[4-(diethylamino)salicylidene]-1,2-phenylenediamine

salicylaldehyde

→

N-[4-(diethylamino)salicylidene]-N′-(salicylidene)-1,2-phenylenediamine

溶剂

ethanol

反应条件

后处理

1. 1
   workup.ADDITIONare added dropwise at 60° C
2. 2
   温度after cooling to room temperature
3. 3
   浓缩concentrated to dryness

实验过程

To a yellowish brown suspension of 0.3 g (1.06 mmol) N-Mono[4-(diethylamino)-salicylidene]-1,2-phenylenediamine from example 30 in 2 ml ethanol are added dropwise at 60° C. 129 mg (112 μl, 1.06 mmol) salicylaldehyde. The reaction slolution is stirred for 5 hours at 75° C. and after cooling to room temperature concentrated to dryness. The crude product is resolved by column chromatography (n-hexane/ethyl acetate 65:35). Yield: 139 mg (34%), colourless oil.

来源