反应 #2314289

反应方程式

1-(4′-(2-tetrahydropyranyloxy)phenyl)-3-bromopropane

triphenylphosphine

→

[3-(4-[2-Tetrahydropyranyloxy]phenyl)propyl]triphenylphosphonium bromide

溶剂

dimethylformamide

反应条件

后处理

1. 1
   温度The reaction mixture is then cooled to room temperature
2. 2
   过滤The white precipitate is filtered
3. 3
   洗涤washed with ethyl acetate
4. 4
   其他dried under vacuum

实验过程

To a solution of 1-(4′-(2-tetrahydropyranyloxy)phenyl)-3-bromopropane 3C (4.2 g) in anhydrous dimethylformamide (11.3 mL) is added triphenylphosphine (6.12 g). The reaction mixture is stirred under nitrogen at 100° C. overnight. The reaction mixture is then cooled to room temperature. The white precipitate is filtered and washed with ethyl acetate, then dried under vacuum.

来源