反应 #2307993

反应方程式

4

tert-butyl N-[1-(cyclopentylcarbonyl)-2-methylbutyl]carbamate

HCl

→

1-cyclopentyl-3-methyl-1-oxo-2-pentanaminium chloride

反应条件

后处理

1. 1
   其他After completion of the reaction the solvent
2. 2
   其他was removed
3. 3
   其他the resulting oil was purified by column chromatography on silical gel
4. 4
   其他The resulting oil was triturated with ether

实验过程

4 (0.18 g, 0.63 mmol) was dissolved in 2 ml HCl (7 N in dioxane). After completion of the reaction the solvent was removed and the resulting oil was purified by column chromatography on silical gel using a chloroform/methanol/water gradient. The resulting oil was triturated with ether.

来源