反应 #2298642

反应方程式

2-ethyl-4-methyl-1,6-dihydro-6-pyrimidone

4-[2-bromoethoxy]nitrobenzene

LiBr

NaH

→

title compound

收率 30.9%

4-[2-[2-Ethyl-4-methyl-6-oxo-1,6-dihydro-1-pyrimidinyl]ethoxy]nitrobenzene

收率 30.9%

反应条件

后处理

1. 1
   其他that described in preparation 1

实验过程

The title compound (5.2 g, 25%) was prepared from 2-ethyl-4-methyl-1,6-dihydro-6-pyrimidone (7.65 g, 55.43 mmol), 4-[2-bromoethoxy]nitrobenzene (15.0 g, 60.97 mmol), LiBr (11.09 g, 127.49 mmol) and 60% NaH (2.76 g, 72.06 mmol) as base by a similar procedure to that described in preparation 1.

来源