反应 #2298639

反应方程式

2-chloromethyl-1-methyl-4-oxo-1,4-dihydroquinazoline

4hydroxybenzaldehyde

K2CO3

→

title compound

收率 65.0%

4-[[1-methyl-4-oxo-1,4-dihydro-2-quinazolinyl]methoxy]benzaldehyde

收率 65.0%

反应条件

后处理

1. 1
   其他that described in preparation 13

实验过程

The title compound (3.64 mg, 65%) was prepared from 2-chloromethyl-1-methyl-4-oxo-1,4-dihydroquinazoline (416 mg, 2.0 mmol) and 4hydroxybenzaldehyde (244 mg, 2.0 mmol) in the presence of K2CO3 (276 mg, 2.0 mmol) as base by a similar procedure to that described in preparation 13.

来源