反应 #2267072

ord-d3e420440800475dbf88c7b2e28ae43e

反应方程式

COc1ccc(CC(C)=O)cc1[N+](=O)[O-]
compound 10
COc1ccc(CC(C)=O)cc1[N+](=O)[O-]
4-Methoxy-3-nitrophenylacetone
COc1ccc(CC(C)=O)cc1N
desired product 11
收率 94.0%
COc1ccc(CC(C)=O)cc1N
3-Amino-4-methoxyphenylacetone
收率 94.0%

溶剂

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    过滤Filtration of the catalyst and evaporation of solvent

实验过程

The mixture of compound 10 (3.0 g, 14.3 mmol) and 10% palladium on carbon (1.6 g) in ethanol (230 ml) was stirred under hydrogen for 3 hours. Filtration of the catalyst and evaporation of solvent gave desired product 11 (2.41 g, 94%).

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US06887867B2uspto-grants-2005_05