反应 #2200633

反应方程式

2,5-difluoro-benzonitrile

4-methylimidazole

potassium carbonate

→

solid

收率 41.0%

5-Fluoro-2-(4-methyl-imidazol-1-yl)-benzonitrile

收率 41.0%

反应条件

后处理

1. 1
   其他After aqueous workup and crystallization from Ethyl acetate the title compound

实验过程

In analogy to example 5a, 2,5-difluoro-benzonitrile was reacted with 4-methylimidazole and potassium carbonate for 20 h at 90° C. After aqueous workup and crystallization from Ethyl acetate the title compound was obtained as a white solid (yield: 41%). MS: m/e=202.3 [M+H]+.

来源