反应 #2200631

反应方程式

5-chloro-2-fluoro-benzonitrile

4-methylimidazole

potassium carbonate

→

solid

收率 63.0%

5-Chloro-2-(4-methyl-imidazol-1-yl)-benzonitrile

收率 63.0%

反应条件

后处理

1. 1
   其他After aqueous workup and crystallization from Ethyl acetate the title compound

实验过程

In analogy to example 5a, 5-chloro-2-fluoro-benzonitrile was reacted with 4-methylimidazole and potassium carbonate for 20 h at 90° C. After aqueous workup and crystallization from Ethyl acetate the title compound was obtained as a white solid (yield: 63%). MS: m/e=218.2 [M+H]+.

来源