反应 #2200620

反应方程式

2-fluoro-5-methoxy-benzonitrile

4-methylimidazole

potassium carbonate

→

solid

收率 72.0%

5-Methoxy-2-(4-methyl-imidazol-1-yl)-benzonitrile

收率 72.0%

反应条件

后处理

1. 1
   其他After aqueous workup and crystallization from Ethyl acetate/diisopropylether the title compound

实验过程

In analogy to example 5a, 2-fluoro-5-methoxy-benzonitrile was reacted with 4-methylimidazole and potassium carbonate for 48 h at 100° C. After aqueous workup and crystallization from Ethyl acetate/diisopropylether the title compound was obtained as a white solid (yield: 72%). MS: m/e=214.1 [M+H]+.

来源