反应 #2200618
ord-048c501b647b414bb21489163d0f40be
反应方程式
2-fluoro-5-methyl-benzonitrile
4-methylimidazole
potassium carbonate
→
title compound
5-Methyl-2-(4-methyl-imidazol-1-yl)-benzonitrile
反应条件
详细条件
See reaction.notes.procedure_details.
实验过程
In analogy to example 5a, 2-fluoro-5-methyl-benzonitrile was reacted with 4-methylimidazole and potassium carbonate for 16 h at 90° C. After aqueous workup the title compound was obtained as a white solid (yield: 48%). MS: m/e=198.4 [M+H]+.