反应 #2195488

反应方程式

hydrochloric acid

Triethylamine

sodium 1,1,3,3,3-pentafluoro-2-(pivaloyloxy)propanesulfonate

dichloromethane

→

trimethylammonium 1,1,3,3,3-pentafluoro-2-(pivaloyloxy)propanesulfonate

收率 75.0%

溶剂

water

反应条件

后处理

1. 1
   workup.ADDITIONwere added, whereupon the mixture
2. 2
   其他The organic layer was separated
3. 3
   洗涤washed with water
4. 4
   洗涤From the organic layer as washed
5. 5
   workup.DISTILLATIONthe dichloromethane was distilled off in vacuum
6. 6
   workup.ADDITIONDiethyl ether was added to the residue for recrystallization
7. 7
   过滤The crystals were filtered
8. 8
   其他dried
9. 9
   其他obtaining the target compound in a yield of 75%

实验过程

Triethylamine was dissolved in cold water. To the solution, hydrochloric acid was added, and sodium 1,1,3,3,3-pentafluoro-2-(pivaloyloxy)propanesulfonate prepared in Synthesis Example 27 and dichloromethane were added, whereupon the mixture was stirred. The organic layer was separated and washed with water. From the organic layer as washed, the dichloromethane was distilled off in vacuum. Diethyl ether was added to the residue for recrystallization. The crystals were filtered and dried, obtaining the target compound in a yield of 75%.

来源