反应 #2171066

反应方程式

water acetone acetonitrile

styrene

N-methylmorpholine-N-oxide

→

1-phenyl-1,2-ethanediol

收率 86.2%

反应条件

后处理

1. 1
   其他was obtained in Example 2
2. 2
   其他a reaction
3. 3
   其他at room temperature
4. 4
   其他for 5 hours
5. 5
   其他After the reaction
6. 6
   过滤was recovered by filtration from the reaction solution
7. 7
   萃取the reaction solution was extracted with ethyl acetate
8. 8
   洗涤the organic layer was washed with water
9. 9
   浓缩concentrated
10. 10
    其他purified by column chromatography

实验过程

To 9 mL of a solvent consisting of water-acetone-acetonitrile (1:1:1) were added 1 g of styrene, 1.5 g of N-methylmorpholine-N-oxide and 1.24 g of the metal oxide carried on the cross-linked polymer compound which was obtained in Example 2, followed by allowing a reaction to take place at room temperature for 5 hours with stirring. After the reaction, the metal oxide carried on the cross-linked polymer compound was recovered by filtration from the reaction solution, and the reaction solution was extracted with ethyl acetate and the organic layer was washed with water, concentrated and purified by column chromatography to give 1.2 g of 1-phenyl-1,2-ethanediol (yield: 86.2%).

来源