反应 #215169

反应方程式

octadecyl bromide

N-(3-aminopropyl)diethanolamine

→

N,N-Bis(2-Hydroxyethyl)-N'-Octadecyl-1,3-Propanediamine

溶剂

benzyl alcohol

反应条件

后处理

1. 1
   其他The benzyl alcohol is removed in vacuo (0.1 mm. Hg, and 75° C.)
2. 2
   洗涤The methylene chloride solution is washed with aqueous sodium hydroxide (1 N)
3. 3
   干燥It is dried (Na2SO4)
4. 4
   浓缩concentrated
5. 5
   workup.DISTILLATIONdistilled

实验过程

A solution of octadecyl bromide (26.65 g., 80 mM.), N-(3-aminopropyl)diethanolamine (105 g., 640 mM.) and benzyl alcohol (120 ml.) is heated at 130° C. for twenty-three hours. The benzyl alcohol is removed in vacuo (0.1 mm. Hg, and 75° C.) and the residue taken up in methylene chloride (250 ml.). The methylene chloride solution is washed with aqueous sodium hydroxide (1 N) then with brine. It is dried (Na2SO4), concentrated, and distilled; b.p. 242°-246° C. at 0.1 mm Hg. The product is a waxy solid.

来源