反应 #2069924

反应方程式

Acetic anhydride

4-isopropylaniline

→

N-Acetyl-4-isopropylaniline

溶剂

chloroform

反应条件

后处理

1. 1
   温度In the course of this, intense heating of the reaction mixture
2. 2
   workup.ADDITIONOn completion of the dropwise addition
3. 3
   浓缩The reaction mixture is concentrated to dryness
4. 4
   其他the resulting, reddish-white solid is recrystallized from hexane

实验过程

Acetic anhydride (26.0 g, 254 mmol) is slowly added dropwise to a solution of 4-isopropylaniline (17.2 g, 127 mmol) in 80 ml of chloroform. In the course of this, intense heating of the reaction mixture occurs. On completion of the dropwise addition, the mixture is stirred at room temperature for another 2 h. The reaction mixture is concentrated to dryness and the resulting, reddish-white solid is recrystallized from hexane.

来源