反应 #2063054

反应方程式

phthalic anhydride

methylamine

→

N-methylphthalimide

溶剂

water

反应条件

后处理

1. 1
   温度The mixture was heated
2. 2
   温度at reflux for four hours
3. 3
   其他after which approximately 50 ml of the aqueous amine was removed by distillation
4. 4
   温度to cool
5. 5
   过滤The resultant precipitate was collected by filtration

实验过程

To a suspension of 25.0 g (0.17 mol) of phthalic anhydride in 200 ml of water was added 30 g (0.38 mol) of a 40% aqueous solution of methylamine. The mixture was heated at reflux for four hours, after which approximately 50 ml of the aqueous amine was removed by distillation and the mixture allowed to cool. The resultant precipitate was collected by filtration to yield 10.3 g of N-methylphthalimide (cyclic imide (b)(4)).

来源