反应 #2028868

反应方程式

Methyl iodide

potassium carbonate

o-thiocresol

hexane

→

desired material

2-methylthioanisole

溶剂

DMF

water

反应条件

后处理

1. 1
   其他The organic layer was separated
2. 2
   干燥dried over magnesium sulfate
3. 3
   浓缩concentrated

实验过程

Methyl iodide (0.5 mL, 8.1 mmol) and potassium carbonate (1.1 g, 8.1 mmol) were added to a solution of o-thiocresol (1.0 g, 8.1 mmol) in 10 mL of DMF. The reaction was stirred at 50° C., for 4 hours and poured into hexane and water. The organic layer was separated, dried over magnesium sulfate and concentrated to afford 1.1 g of desired material.

来源